{"id":27227,"date":"2026-06-15T10:25:21","date_gmt":"2026-06-15T08:25:21","guid":{"rendered":"https:\/\/lluita.org\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\/"},"modified":"2026-06-15T10:36:13","modified_gmt":"2026-06-15T08:36:13","slug":"lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent","status":"publish","type":"post","link":"https:\/\/lluita.org\/en\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\/","title":{"rendered":"The Thalassa clinical trial completes the final administration of treatment in patients with long COVID"},"content":{"rendered":"

From the Fight Against Infections Foundation, we have completed the final administration of treatment in the Thalassa clinical trial<\/a>, a phase II study<\/strong> designed to evaluate the safety and efficacy of a new therapeutic strategy against long COVID.<\/strong> This milestone marks a significant step within the project, following months of participant recruitment and treatment, and signals the close of the intervention phase.<\/p>\n

\n

The Thalassa trial, led by the Foundation in collaboration with PharmaMar<\/a>, aims to analyse the potential of plitidepsin<\/strong> to improve symptoms in people with long COVID. This is a marine-derived active compound, obtained from an ascidian, which works by triggering cell death through a process known as apoptosis.<\/p>\n

The study has been made possible thanks to the participation of 90 adult individuals<\/strong> with long COVID, who received either the treatment or a placebo. With the completion of treatment administration, the study now enters a new phase.<\/p>\n

Although the intervention phase has been completed, participant follow-up will continue until September<\/strong>, with the aim of assessing clinical progression and collecting detailed data on response to the medication. This analysis will be key to determining whether this therapeutic strategy can become an effective option<\/strong> for a condition that, to date, still lacks established specific treatments.<\/p>\n

Long COVID mainly affects individuals who experienced a mild or moderate initial SARS-CoV-2 infection<\/strong>, most of whom did not require hospitalisation. It is more common in women, with an average age between 40 and 50, and presents with a wide range of symptoms that can affect multiple organs and body systems. In many cases, these symptoms may persist for months or even years, with a significant impact on patients\u2019 quality of life.<\/p>\n

It is estimated that in Catalonia there are approximately 200,000 people living with long COVID, representing around 10% of those who have had the infection.<\/strong> At national level, this figure could reach up to 2 million people affected.<\/p>\n

The final results of the study are expected in 2027<\/strong>, as a thorough analysis of all the collected data will be required to ensure robustness and scientific rigour.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

From the Fight Against Infections Foundation, we have completed the final administration of treatment in the Thalassa clinical trial, a phase II study designed to evaluate the safety and efficacy of a new therapeutic strategy against long COVID. This milestone marks a significant step within the project, following months of participant recruitment and treatment, and […]<\/p>\n","protected":false},"author":8,"featured_media":27224,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[264],"class_list":["post-27227","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-en"],"acf":[],"yoast_head":"\nThe Thalassa clinical trial completes the final administration of treatment in patients with long COVID - Fundaci\u00f3 Lluita contra les Infeccions<\/title>\n<meta name=\"description\" content=\"Clinical trial Thalassa: treatment administration in patients with long COVID has been completed, and the study now enters the follow-up phase to assess its efficacy and safety.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lluita.org\/en\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Thalassa clinical trial completes the final administration of treatment in patients with long COVID\" \/>\n<meta property=\"og:description\" content=\"Clinical trial Thalassa: treatment administration in patients with long COVID has been completed, and the study now enters the follow-up phase to assess its efficacy and safety.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lluita.org\/en\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\/\" \/>\n<meta property=\"og:site_name\" content=\"Fundaci\u00f3 Lluita contra les Infeccions\" \/>\n<meta property=\"article:published_time\" content=\"2026-06-15T08:25:21+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-15T08:36:13+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lluita.org\/custom\/uploads\/2026\/06\/Assaig-clinic-Thalassa-1024x546.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"546\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"LLUITA Admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"LLUITA Admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\\\/\"},\"author\":{\"name\":\"LLUITA Admin\",\"@id\":\"https:\\\/\\\/lluita.org\\\/#\\\/schema\\\/person\\\/ebbfd4b21b6e55289e039158312b195a\"},\"headline\":\"The Thalassa clinical trial completes the final administration of treatment in patients with long COVID\",\"datePublished\":\"2026-06-15T08:25:21+00:00\",\"dateModified\":\"2026-06-15T08:36:13+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\\\/\"},\"wordCount\":350,\"image\":{\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/lluita.org\\\/custom\\\/uploads\\\/2026\\\/06\\\/Assaig-clinic-Thalassa-scaled.png\",\"articleSection\":[\"COVID-19\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\\\/\",\"url\":\"https:\\\/\\\/lluita.org\\\/en\\\/lassaig-clinic-thalassa-completa-lultima-administracio-de-tractament-en-pacients-amb-covid-persistent\\\/\",\"name\":\"The Thalassa clinical trial completes the final administration of treatment in patients with long COVID - 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