{"id":27829,"date":"2026-09-25T17:33:37","date_gmt":"2026-09-25T15:33:37","guid":{"rendered":"https:\/\/lluita.org\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\/"},"modified":"2026-09-25T18:18:57","modified_gmt":"2026-09-25T16:18:57","slug":"un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies","status":"publish","type":"post","link":"https:\/\/lluita.org\/en\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\/","title":{"rendered":"International study warns of an increase in Campylobacter bloodstream infections among people with immunodeficiencies"},"content":{"rendered":"<p>An international study involving data from 261 bloodstream infections caused by bacteria of the genus <em>Campylobacter<\/em> has found that <strong>people with humoral immunodeficiencies<\/strong>, which are immune system disorders that affect antibody production, are at <strong>particularly high risk of recurrent infections caused by this bacterium<\/strong>. The research, conducted with the participation of researchers from the <span class=\"___xxxjie0 f1w7gpdv f1gqqdtu\" data-wra=\"1\"><a class=\"fui-Link fai-bebop ___1myvvpj f2hkw1w f3rmtva f1ewtqcl f16muhyy f1k6fduh f1w7gpdv f1mo0ibp fjoy568 ff5ikls f1s184ao f1mk8lai fnbmjn9 f1o700av f13mvf36 f33ey8m f9n3di6 f1ids18y f1tx3yz7 f1bwia3u f1eh06m1 f1xeumsx fhgqx19 f1olyrje f1p93eir f1nev41a f132whgj f1v74mp6 f1tsf1ni fnq52rx f16zlvvm\" tabindex=\"0\" href=\"https:\/\/lluita.org\/en\/\" target=\"_blank\" rel=\"noopener noreferrer\" data-tabster=\"{&quot;restorer&quot;:{&quot;type&quot;:1}}\">Fight Infections Foundation<\/a><\/span>, also warns that <strong>antibiotic resistance<\/strong> in some species of this bacterium may exceed 90%.<\/p>\n<div>\n<p>The study, published in the journal <span class=\"___xxxjie0 f1w7gpdv f1gqqdtu\" data-wra=\"1\"><a class=\"fui-Link fai-bebop ___1myvvpj f2hkw1w f3rmtva f1ewtqcl f16muhyy f1k6fduh f1w7gpdv f1mo0ibp fjoy568 ff5ikls f1s184ao f1mk8lai fnbmjn9 f1o700av f13mvf36 f33ey8m f9n3di6 f1ids18y f1tx3yz7 f1bwia3u f1eh06m1 f1xeumsx fhgqx19 f1olyrje f1p93eir f1nev41a f132whgj f1v74mp6 f1tsf1ni fnq52rx f16zlvvm\" tabindex=\"0\" href=\"https:\/\/academic.oup.com\/ofid\/advance-article\/doi\/10.1093\/ofid\/ofag380\/8713478\" target=\"_blank\" rel=\"noopener noreferrer\" data-tabster=\"{&quot;restorer&quot;:{&quot;type&quot;:1}}\"><em>Open Forum Infectious Diseases<\/em><\/a><\/span>, analysed cases diagnosed between 2009 and 2024 across 27 hospitals in five countries: Spain, Italy, France, the United Kingdom and Brazil. This makes it one of the largest studies on <em>Campylobacter<\/em> bacteraemia described to date.<\/p>\n<p>Although this bacterium is primarily known for <strong>causing gastroenteritis and diarrhoea<\/strong>, in some cases it can enter the bloodstream and cause serious infections. <strong>This risk is particularly significant in immunocompromised people.<\/strong> In fact, almost <strong>two-thirds of the cases analysed involved patients with some form of immunodeficiency.<\/strong><\/p>\n<h3>Nine out of ten recurrent infections occur in patients with antibody deficiencies<\/h3>\n<p>The researchers observed that recurrent infections occurred in 8% of cases. However, the risk was considerably higher among patients with <strong>immune system disorders that impair antibody production<\/strong>, who accounted for 19 of the 21 recurrent episodes recorded in the study.<\/p>\n<p>This phenomenon was particularly common among <strong>people who have difficulty producing antibodies<\/strong>, a key component of the immune system&#8217;s defence against infections, as well as among patients with blood disorders who had received treatments that affect these defences.<\/p>\n<p>In addition, people with humoral immunodeficiencies were more likely to have a history of <em>Campylobacter<\/em> infections and previous episodes of bacteraemia, reinforcing the key role of antibodies in controlling this microorganism.<\/p>\n<h3>More than 90% of Campylobacter coli strains are resistant to antibiotics<\/h3>\n<p>The study also describes an increase in cases caused by <em>Campylobacter coli<\/em>, which <strong>rose from accounting for 12% of episodes during the earlier years of the study to almost 27% in the most recent period.<\/strong><\/p>\n<p>The results show that this species has very high levels of resistance to antibiotics commonly used to treat these infections. Specifically, <strong>more than 90% of the <em>Campylobacter coli<\/em> strains analysed were resistant to ciprofloxacin<\/strong>, while more than half were resistant to azithromycin, two of the antibiotics most commonly used to treat this bacterium.<\/p>\n<p>The authors point out that this situation represents a growing clinical challenge and highlight the need to optimise treatment strategies for the most vulnerable patients.<\/p>\n<h3>An infection with a low mortality rate but a high recurrence rate<\/h3>\n<p>Although <strong>overall mortality at 30 days was below 10%<\/strong>, the researchers highlight that <strong>the main problem in this patient group was recurrence of the infection<\/strong>, which can occur weeks or even months after the initial episode.<\/p>\n<p>According to the authors, the findings highlight the need for further studies to better understand the mechanisms that contribute to these recurrent infections and to determine the optimal duration of antibiotic treatment to prevent them.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>An international study involving data from 261 bloodstream infections caused by bacteria of the genus Campylobacter has found that people with humoral immunodeficiencies, which are immune system disorders that affect antibody production, are at particularly high risk of recurrent infections caused by this bacterium. The research, conducted with the participation of researchers from the Fight [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":27825,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[277],"class_list":["post-27829","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-infections-immunocompromised-patients"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.5 (Yoast SEO v28.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>International study warns of an increase in Campylobacter bloodstream infections among people with immunodeficiencies - Fundaci\u00f3 Lluita contra les Infeccions<\/title>\n<meta name=\"description\" content=\"An international study warns of recurrent Campylobacter infections in people with immunodeficiencies and high levels of antibiotic resistance.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lluita.org\/en\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"International study warns of an increase in Campylobacter bloodstream infections among people with immunodeficiencies\" \/>\n<meta property=\"og:description\" content=\"An international study warns of recurrent Campylobacter infections in people with immunodeficiencies and high levels of antibiotic resistance.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lluita.org\/en\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\/\" \/>\n<meta property=\"og:site_name\" content=\"Fundaci\u00f3 Lluita contra les Infeccions\" \/>\n<meta property=\"article:published_time\" content=\"2026-09-25T15:33:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-25T16:18:57+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lluita.org\/custom\/uploads\/2026\/09\/Campylobacter-1024x683.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"683\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"LLUITA Admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"LLUITA Admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\\\/\"},\"author\":{\"name\":\"LLUITA Admin\",\"@id\":\"https:\\\/\\\/lluita.org\\\/#\\\/schema\\\/person\\\/ebbfd4b21b6e55289e039158312b195a\"},\"headline\":\"International study warns of an increase in Campylobacter bloodstream infections among people with immunodeficiencies\",\"datePublished\":\"2026-09-25T15:33:37+00:00\",\"dateModified\":\"2026-09-25T16:18:57+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\\\/\"},\"wordCount\":491,\"image\":{\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/lluita.org\\\/custom\\\/uploads\\\/2026\\\/09\\\/Campylobacter.jpg\",\"articleSection\":[\"Infections in immunocompromised patients\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/lluita.org\\\/en\\\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\\\/\",\"url\":\"https:\\\/\\\/lluita.org\\\/en\\\/un-estudi-internacional-alerta-de-laugment-de-les-infeccions-sanguinies-per-campylobacter-en-persones-amb-immunodeficiencies\\\/\",\"name\":\"International study warns of an increase in Campylobacter bloodstream infections among people with immunodeficiencies - 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